This paper presents an overview of silver nanoparticles (Ag NPs) preparation by green synthesis approaches that have advantages over conventional methods involving chemical agents associated with environmental toxicity and also explains its application in the cure of Rheumatoid arthritis. We have used Night Jasmine (Nyctanthes arbor-tristis), one of the best medicinal plants to synthesis Ag NPs. The plant extract contain some biomolecules like proteins carbohydrates etc., which act as both reducing and capping agents forming stable and shape-controlled Ag NPs. The basic principle behind the synthesis is that the silver (Ag+) of AgNO3 is reduced to Ag0 by the bio-molecules present in the extract. Rather than applying the conventional method of using micro waves to induce the reduction reaction, we have used direct sunlight as the inducer by which the reduction is faster than the former. The synthesized silver nanoparticles were characterized with UV-Visible spectroscopy, X-ray Diffraction (XRD), scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). The results of all these analysis were shown. Our work mainly concerns about the cure for Rheumatoid arthritis so, we have checked the Nano-particles for the Anti-Arthritic activity and the results were positive. The procedure for Invitro analysis of anti-arthritic activity and its result are clearly shown.